Saponaro Andrea Cosimo
Ricercatore a Tempo Determinato (B)
Settore scientifico-disciplinare
BIOS-06/A - Fisiologia
Gruppo scientifico-disciplinare / settore concorsuale
05/BIOS-06 - FISIOLOGIA
Competenze e ambito di ricerca
Contacts
Sede di lavoro
Numero di telefono dell'ufficio
E-mail di ateneo
Office hours
su appuntamento
Luogo di ricevimento
via Balzaretti 9, oppure su MS Teams
Teaching - Programme courses
Bachelors and masters
A.A. 2025/2026
A.A. 2024/2025
A.A. 2023/2024
A.A. 2022/2023
A.A. 2021/2022
A.A. 2019/2020
A.A. 2018/2019
Research
Publications
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Structure mirroring function: What's the ‘matter’ with the funny current? / A. Saponaro, D. Difrancesco. - In: THE JOURNAL OF PHYSIOLOGY. - ISSN 0022-3751. - (2025), pp. 1-20. [Epub ahead of print] [10.1113/jp287209]
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Structural determinants of ivabradine block of the open pore of HCN4 / A. Saponaro, J.H. Krumbach, A. Chaves-Sanjuan, A.S. Sharifzadeh, A. Porro, R. Castelli, K. Hamacher, M. Bolognesi, D. Difrancesco, O.B. Clarke, G. Thiel, A. Moroni. - In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - ISSN 1091-6490. - 121:27(2024 Jul 02), pp. e2402259121.1-e2402259121.8. [10.1073/pnas.2402259121]
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A high affinity switch for cAMP in the HCN pacemaker channels / A. Porro, A. Saponaro, R. Castelli, B. Introini, A.H. Alkotob, G. Ranjbari, U. Enke, J. Kusch, K. Benndorf, B. Santoro, D. Difrancesco, G. Thiel, A. Moroni. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - 15:1(2024 Jan), pp. 843.1-843.14. [10.1038/s41467-024-45136-y]
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A Photoactivatable Version of Ivabradine Enables Light-Induced Block of HCN Current In Vivo / A. Porro, E. Armano, F. Brandalise, R. Appiani, M. Beltrame, A. Saponaro, C. Dallanoce, K. Nakajo, K. Ryu, R. Leone, G. Thiel, M. Pallavicini, A. Moroni, C. Bolchi. - In: JOURNAL OF MEDICINAL CHEMISTRY. - ISSN 1520-4804. - (2024), pp. 1-13. [Epub ahead of print] [10.1021/acs.jmedchem.4c01047]
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Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block / J. Krumbach, D. Bauer, A.S. Sharifzadeh, A. Saponaro, R. Lautenschläger, K. Lange, O. Rauh, D. Difrancesco, A. Moroni, G. Thiel, K. Hamacher. - In: JOURNAL OF GENERAL PHYSIOLOGY. - ISSN 0022-1295. - 155:10(2023), pp. e202313364.1-e202313364.22. [10.1085/jgp.202313364]