Broggini Luca
Post-doctoral fellow (B)
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Research
Publications
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A conformational fingerprint for amyloidogenic light chains / C. Paissoni, S. Puri, L. Broggini, M.K. Sriramoju, M. Maritan, R. Russo, V. Speranzini, F. Ballabio, M. Nuvolone, G. Merlini, G. Palladini, S.-.D. Hsu, S. Ricagno, C. Camilloni. - In: ELIFE. - ISSN 2050-084X. - 13:(2025 Mar 03), pp. RP102002.1-RP102002.21. [10.7554/eLife.102002]
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The critical role of the variable domain in driving proteotoxicity and aggregation in full-length light chains / S. Puri, A. Gadda, I. Polsinelli, M.M. Barzago, A. Toto, M.K. Sriramoju, C. Visentin, L. Broggini, D.M. Valérie Bonnet, R. Russo, A. Chaves-Sanjuan, G. Merlini, M. Nuvolone, G. Palladini, S. Gianni, S.D. Hsu, L. Diomede, S. Ricagno. - In: JOURNAL OF MOLECULAR BIOLOGY. - ISSN 0022-2836. - (2025), pp. 1-33. [Epub ahead of print] [10.1016/j.jmb.2025.168958]
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An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent / M. Alberti, G. Poli, L. Broggini, S. Sainas, M. Rizzi, D. Boschi, D.M. Ferraris, E. Martino, S. Ricagno, T. Tuccinardi, M.L. Lolli, R. Miggiano. - In: ACTA CRYSTALLOGRAPHICA. SECTION D, STRUCTURAL BIOLOGY. - ISSN 2059-7983. - 80:6(2024 Jun 01), pp. 386-396. [10.1107/s2059798324004066]
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Multi-eGO: An in silico lens to look into protein aggregation kinetics at atomic resolution / E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Bačić Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni. - In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. - ISSN 0027-8424. - 119:26(2022 Jun 28), pp. e2203181119.1-e2203181119.10. [10.1073/pnas.2203181119]
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L- to D-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics / F. Ballabio, L. Broggini, C. Paissoni, X. Han, K. Peqini, B.M. Sala, R. Sun, T. Sandalova, A. Barbiroli, A. Achour, S. Pellegrino, S. Ricagno, C. Camilloni. - In: ACS OMEGA. - ISSN 2470-1343. - 7:11(2022 Mar 22), pp. 9622-9635. [10.1021/acsomega.1c06964]